To expand on the quick answer the V2 has a good sized detached control panel and two options where the spool holder can be mounted. Depending on where you mount the spool holder will determine how much space you need. For the sake of simplicity I’m going to refer to these two configurations as horizontal and vertical.
With either setup there are three aspects of the printer to take into consideration.
In the horizontal setup, which is the one I use, the spool holder is attached to the top of the control unit which sits to the left of the printer itself or to right if you prefer. This setup does require more horizontal space, hence the name.
While I do use this setup there is one issue to take into consideration and that is filament guidance. Since the filament is coming from one side of the printer as opposed from the top it’s a good idea to install a filament guide on top of the printer that brings the filament up above the frame and then allows it to go straight down into the printer. This setup will need at minimum a space 54 cm / 21.25 inches deep, 44 cm / 17.3 inches tall, and 68 cm / 26.8 inches wide. See illustrations below.
In the vertical setup the spool holder is attached to the top of the printer frame. This setup does require more vertical space, hence the name.
I’m not a fan of this setup because having the weight of a filament spool, especially a new one, on top a constantly vibrating printer, I think, introduces some sympathetic vibrations into the frame itself and can thus adversely affect the print. This setup will need at minimum a space 54 cm / 21.25 inches deep, 62 cm / 24.4 inches tall, and 62 cm / 24.4 inches wide. See illustrations below.
Special thanks to SpaceGK for the comment on Episode 6, thank you!